| Title： | Consensus of experts on radionuclide therapy of bone metastases |
| Edition： | Original |
| Classification： | Experts consensus |
| Field： | Diagnosis and Treatment |
| Countries and regions： | China |
| Guidelines users： | |
| Evidence classification method： | GRADE (Grading of Recommendations, Assess, Development and Evaluation) |
| Development unit： | Nuclear Medicine Branch of Chinese Clinical Oncology Society；Nuclear Medicine Branch of Chinese Medical Association； Nuclear Medicine and Molecular Imaging Special Committee of Zhejiang Anti-Cancer Association |
| Registration time: | 2024-04-17 |
| Registration number： | PREPARE-2024CN538 |
| Purpose of the guideline: | Bone metastasis is one of the most common complications of malignant tumors. Autopsy shows that 85% of malignant tumors have bone metastasis, and the incidence of bone metastasis in patients with prostate cancer, breast cancer and lung cancer can reach more than 80%. The survival time of patients with advanced cancer continues to prolong, and the risk of bone metastasis and bone-related events (Skeletal-related events,SREs) increases significantly. Bone metastasis of malignant tumor can lead to a series of bone-related events, such as intractable bone pain, dysfunction, pathological fracture, hypercalcemia and so on. In particular, extensive bone metastasis and intractable bone pain seriously affect the prognosis and quality of life of patients. Early detection of bone metastases is very important for accurate clinical staging, selection of follow-up treatment strategies, reducing the risk of complications and improving the quality of life. With the continuous improvement of diagnostic technology and treatment level of malignant tumors, the basic and clinical research of bone metastasis has made great progress, especially in the early diagnosis and effective treatment of bone metastases. People pay more and more attention to the comprehensive treatment of malignant tumor after metastasis to bone. At present, the common treatment methods of bone metastases are surgery, external radiation therapy, radionuclide therapy, hormone therapy, chemical drug therapy and traditional Chinese medicine therapy and so on. Among them, targeted radionuclide radiotherapy is a rapidly developing method in recent years, which has the advantages of good curative effect, simple method and less side effects. therefore, this method has become a new and effective treatment for bone metastasis and pain caused by tumor. This consensus brings together experts from nuclear medicine, orthopaedics, oncology, anaesthesia and pain, imaging, radiotherapy, mental health and other multidisciplinary experts, focusing on radionuclide therapy and highlighting multidisciplinary MDT comprehensive evaluation and treatment. |
Latest registration
